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Informed consents were obtained from all patients. National Center for Biotechnology InformationU. Oncol Rep. Published online Feb China Find articles by Yifan Li. China Find articles by Jiajing Liu. China Find articles by Zhou Lu. China Find DCS DCS S817 by Mingfang Lu. China Find articles by Jie Gu. China Find articles by Ronghua Liu.
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Author information Article notes DCS DCS S817 and License information Disclaimer. Correspondence to: China, E-mail: Received Oct 29; Accepted Feb This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs Licensewhich permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.
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This article has been cited by other articles in PMC. Abstract Dendritic cells DCsas professional antigen-presenting cells are essential for the initial activation of adaptive antitumor immunity.
CD1d, tumor, natural killer T cell, T cells, dendritic cells. Introduction DCS DCS S817 cells DCs are highly specialized professional antigen-presenting cells APCs that link antigen-independent innate immunity and antigen-specific adaptive immunity, essential for the initial activation of antitumor immunity 12. Materials and methods Clinical samples The adjacent normal and neoplastic tissues were obtained from nine lung cancer patients 2 females and 7 malesfemale, 39 years old; male, 64 years old; male, 64 years old; male, 66 years old; female, 39 years old; male, 69 years old; male, 37 years old; male, 61 years old; and male, 65 years old; the mean age of the patients was 56 years who underwent complete surgical resections at Zhongshan Hospital Shanghai, China.
Open in a separate window. Figure 1.
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CD1d is mainly expressed on DCs in the presence of tumors CD1d is an important antigen-presenting molecule. Figure 2. Figure 3. Figure 4.
Figure 5. Figure 6. Discussion CD1d, an MHC-I like molecule can present phospholipid and glycosphingolipid antigens Ags to natural killer T DCS DCS S817 cells, which regulate nearly all aspects of both the innate and adaptive immune responses.
Supplementary Material Supporting Data: Click here to view. Authors contributions YL and CZ completed DCS DCS S817 trial procedures, data analysis and were major contributors in writing the manuscript. Ethics approval and consent to participate The study was approved by the Zhongshan Hospital Research Ethics Committee. Patient consent for publication Not applicable.
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Competing interests The authors declare that they have no competing interests. References 1.
Escors D. Tumour immunogenicity, antigen presentation and immunological barriers in cancer immunotherapy. New J Sci. Dysfunction of antigen processing and presentation by dendritic cells in cancer. Mol Immunol.
Epub ahead of print. S 18doi: Perspectives on the clinical development of immunotherapy in prostate cancer. Asian J Androl. Immuno-modulators enhance antigen- specific immunity and anti-tumor effects of mesothelin-specific chimeric DNA vaccine through promoting DC maturation. Cancer Lett. Turning tumour cells into antigen presenting cells: The next step to improve cancer immunotherapy? Eur J DCS DCS S817. Download DCS DCS S driver for Sound card, different software versions available here. DCS Multimedia DCS S driver. DCS Multimedia Sound Card Drivers.
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